Brian Shirts, M.D., is a board-certified physician and the assistant director of UW Medicine Genetics and Solid Tumor and Informatics at UW Laboratory Medicine. He earned his M.D. and Ph.D. at the University of Pittsburgh and is board-certified in Clinical Pathology and Molecular Genetic Pathology. Dr. Shirts specializes in genetic testing for hereditary cancer risk and other complex hereditary traits. His clinical and research interests include improving the detection and classification of rare mutations, particularly in familial cancer genes, and the clinical classification of rare genetic variants of uncertain significance.